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Typically red blood cells contain an iron-rich protein, haemoglobin, that carries oxygen. People with Sickle Cell Disease inherit genes with instructions, or codes, for abnormal haemoglobin. This abnormal haemoglobin makes these red blood cells - sickle or crescent-like making them rigid and sticky, causing obstruction in normal blood flow and, at times, occluding complete blood supply to organs leading to sickle cell crisis, which commonly presents with acute pain frequently managed with the help of opioids. Dr Saswinder Kaur, Senior Resident, Department of Psychiatry, Amrita Hospital, Faridabad, explains the situation may begin within the first year of life and continue throughout life. People With SCD People with SCD must remain vigilant throughout their life, which can be emotionally and physically draining. They may also have trouble coping with pain, fatigue, frequent medical visits and hospitalizations. The limitations imposed on children because of susceptibility to infection ...